Detection of antibodies to gliadin, one of the major protein components of gluten, is a sensitive assay useful in diagnosing celiac disease. However, gliadin antibodies may be found in individuals without celiac disease; thus gliadin antibody assays are less specific than assays measuring antibodies to endomysium and transglutaminase. Recent work has revealed that gliadin-reactive antibodies from celiac patients bind to a very limited number of specific epitopes on the gliadin molecule. Further, deamidation of gliadin results in enhanced binding of gliadin antibodies. Based on this information, assays using deamidated gliadin peptides bearing the celiac-specific epitopes have much higher diagnostic accuracy for celiac disease when compared to standard gliadin antibody assays.
Gliadin (Deamidated Peptide) Antibody (IgG, IgA)
Blood Test Types
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Certain lab tests may come back in the "normal" range. Reference ranges do not always mean "optimal." Patients may still experience symptoms in the "normal" range. It is important to speak with a qualified health practitioner regarding normal vs optimal.
This lab test can be purchased without a physician and drawn at a Quest Diagnostics location. A small draw fee of $ 8 will be applied at checkout. There are no other "hidden" fees unless noted on the lab test.
Currently, NY, NJ, and RI state laws prohibit direct-access testing. This lab test cannot be conducted at lab locations within these states at this time.